Ceftriaxone + Sulbactam Injection

Ceftriaxone + Sulbactam Injection comes with the branding “CEFOVA-S” and is a class of medication known as ‘antibiotics’ and is prescribed for treating bacterial infections. Bacterial infection occurs due to the growth of harmful bacteria within or on the body. Harmful bacteria make chemicals called toxins, which destroy tissue and you ill. Signs of bacterial infection depend on the organ infected with bacteria.

Ceftriaxone + Sulbactam Injection is a drug combination of two drugs: Ceftriaxone and Sulbactam. Ceftriaxone is a cephalosporin antibiotic. It is bactericidal (kills bacteria). It inhibits the formation of the cell wall (the outer covering of bacteria, which is crucial for its survival) by inhibiting protein synthesis. Sulbactam prevents the action of beta-lactamase. Beta-lactamase is an enzyme secreted by bacteria that can make antibiotics (ceftriaxone).

Medical Benefits

• Ceftriaxone is a cephalosporin antibiotic, while Sulbactam is a beta-lactamase inhibitor.
• It possesses broad-spectrum activity and acts against both gram-positive and gram-negative bacteria.
• It makes the drug effective against several severe bacterial infections, such as infections of the blood (septicemia), the bones (osteomyelitis), the heart valves (endocarditis), the membranes covering the brain (meningitis), acute bacterial otitis media (middle ear infection) and the lining of the abdomen (peritonitis) and to avert and treat infections after operations.

Directions For Use

• Read the instructions carefully on the label.
• Wash your hands and the injection site.
• Prepare the syringes and medicines.
• Inject in the appropriate place, i.e intravenous, intramuscular, or subcutaneous
• Dispose of the needle in the trash.
• Inject away from the infecting site.

Storage

• Store this Ceftriaxone + Sulbactam Injection away from light in a cool, dry place.
• Make sure that the injection is shielded from different materials to ensure it remains protected from contamination at all times.
• Keep it beyond the reach of the children and never use it after its expiry date.

Precautions

• It can interact with vaccines (cholera vaccine), estrogens (Ethinyl estradiol), penicillin antibiotics (mezlocillin and azlocillin), aminoglycoside antibiotics (amikacin, streptomycin, neomycin, and gentamicin), immunosuppressants (cyclosporine) and medication for the treatment of gout (probenecid).
• It must be taken cautiously in kidney disease, diabetes, convulsions, liver disorders, gastrointestinal disorders, and bleeding disorders.
• Drinking alcohol should be avoided to prevent unwanted side effects.
• Ceftriaxone + Sulbactam Injection should not be used during pregnancy unless essential.
• Tell your doctor if you are breastfeeding. Your doctor can prescribe this medication if the potential benefits outweigh the disadvantages.
• This medication can reduce your alertness and vision or make you drowsy and dizzy. So consult a doctor before its intake.
• Use it cautiously if you have impaired liver function because there is a higher risk of worsening your condition.

Side Effects

• Elevated liver enzymes
• Skin rash
• Anaphylaxis
• Nausea
• Diarrhoea

Frequently Asked Questions (FAQs)

Can I discontinue this medication abruptly?

No, don’t discontinue suddenly. Even when you start feeling better, you should complete the full treatment to ensure the infection disappears.

Can I take this injection if I am penicillin allergic? 

No, you may also be sensitive to this medication if you are penicillin allergic. Consult your physician first.

Can this medicine cause an allergic response? 

Yes, some individuals might develop rashes, swelling, or difficulty breathing. If you are allergic to other antibiotics, inform your doctor.

Can this composition lead to diarrhoea?

Yes, it may. It can irritate your stomach by interfering with the good bacteria. Have fluids, take probiotics, and visit your doctor if it becomes severe or does not go away.

How long does this medicine take to work?

It begins to work within a few hours. You might feel better within a couple of days, depending on the severity of the infection.

What if I don’t improve after using it?

If you’re not getting better, the infection probably isn’t responding to the medication. See your doctor—they might need to switch your treatment.